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Scientists prove cell-cultured meat products can offer enhanced nutrition compared to conventionally produced meat

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A group of researchers at Tufts University have genetically engineered cow muscle cells to produce plant nutrients not natively found in beef cells. Using the same carotenoid pathway exploited in golden rice, they coaxed bovine cells into producing beta carotene—a provitamin usually found in carrots and tomatoes.

In doing so, they demonstrated that cell-cultured meat might be able to surpass the nutritional profile of conventionally farmed meat.

“Cows don’t have any of the genes for producing beta carotene,” said Andrew Stout, lead author of the study and Biomedical Engineering Ph.D. student at Tufts University. “We engineered cow muscle cells to produce this and other phytonutrients, which in turn allows us to impart those nutritional benefits directly onto a cultured meat product in a way that is likely infeasible through animal transgenics and conventional meat production.”

These findings, published in the journal Metabolic Engineering, are proof of principle for using genetic engineering and cellular agriculture to create novel foods. Rather than simply mimicking meat currently found in the grocery store, cell-cultured meat products are capable of assuming different shapes, textures, nutritional profiles, and bioactivities.

One such feature is carcinogenicity, or rather, the lack thereof.

“We saw a reduction in lipid oxidation levels when we cooked a small pellet of these cells when they were expressing and producing this beta carotene,” said Stout. “Because that lipid oxidation is one of the key mechanistic proposals for red and processed meats’ link to diseases such as colorectal cancer, I…

Science X staff

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